This lecture will examine the current possibilities for the technological enhancement of human beings, including genetic enhancement and enhancement of athletic performance using drugs. I will examine the argument that when an enhancement improves a person's life, that is, increases his or her well-being, we have a moral obligation to provide that enhancement. I will examine a range of objections, including objections that we cannot know what kinds of biological modifications will improve a person's life and that we should not interfere with human nature. I will examine the claim that there is an important distinction between therapy and enhancement, and that we should only provide therapy not enhancement. Finally, I will consider the objection that enhancements which provide mainly competitive advantage, such as enhancement in sport, should not be permitted.